Paclitaxel hypersensitivity reactions: A role for docetaxel substitution
نویسندگان
چکیده
منابع مشابه
Rapid desensitization for hypersensitivity reactions to paclitaxel and docetaxel: a new standard protocol used in 77 successful treatments.
OBJECTIVE Administration of paclitaxel is associated with hypersensitivity reactions (HSRs) in up to 9% of patients despite premedication. The purpose of this study was to evaluate the effectiveness of a standardized desensitization protocol in patients with HSRs to taxanes, based on our experience with carboplatin desensitization. METHODS We analyzed seventeen consecutive patients with docum...
متن کاملSuccessful treatment with nab-paclitaxel after hypersensitivity reaction to paclitaxel and docetaxel☆
•First case report of successfully treating severe paclitaxel and docetaxel hypersensitivity reaction with nab-paclitaxel•We demonstrated that nab-paclitaxel is a safe taxane chemotherapy treatment option for patients who could not tolerate paclitaxel or docetaxel.
متن کاملRapid desensitization for hypersensitivity reactions to chemotherapeutic drugs; a case series
Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...
متن کاملRapid desensitization for hypersensitivity reactions to chemotherapeutic drugs; a case series
Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...
متن کاملUniversal tolerance of nab-paclitaxel for gynecologic malignancies in patients with prior taxane hypersensitivity reactions
OBJECTIVE To report on the incidence of nab-paclitaxel hypersensitivity reactions (HSRs) in patients with prior taxane HSR. METHODS From 2005 to 2015, all patients who received nab-paclitaxel for a gynecologic malignancy were identified. Chart abstraction included pathology, prior therapy, indication for nab-paclitaxel, dosing, response, toxicities including any HSR, and reason for discontinu...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1998
ISSN: 0923-7534
DOI: 10.1023/a:1008272114546